Principles and main aspects of animal experiments

Subject: Principles and main aspects of animal experiments
NEPTUN code: AOG518806
year, semester: 1st and 2nd semester, III-V. year
Óraszám: 20
Entrance conditions:  “Basic Surgical Techniques” exam  
Lecturers:  Prof. Norbert Németh, M.D., Ph.D., D.Sc., Dr. Deák Ádám,  M.D., Ph.D. email:

Aim of the course:

Being familiar with the legal background, ethical aspects, principles and aspects of experimental design of animal experiments that are still essential in biomedical research, in accordance with Hungarian law and EU regulations, as well as the recommendations of the Federation of European Laboratory Animal Science Associations (FELASA).


  1. History of animal experiments. The role of animal experiments in biomedical research.
  2. Legal & ethical aspects, and authorization of animal experiments.
  3. Principles of the planning and implementation of animal experiments.
  4. Genetic standardization of laboratory animals.
  5. Microbiological standards. Hygiene levels and categories of animal facilities.
  6. Construction of animal facilities. Care and handling of experimental/laboratory animals.
  7. Comparative anatomy and physiology of experimental/laboratory animals used in biomedical research.
  8. Anesthesia of experimental/laboratory animals. Monitoring of the vital parameters.
  9. Blood sampling techniques in animal experiments.
  10. In vivo, ex vivo, in vitro techniques and models.

Reading materials:

Lecture pdf and e-learning materials

Recommended materials:

L.F.M. van Zuthpen, V. Baumans, A.C. Beynen (eds): Principles of Laboratory Animal Science. Elsevier 2001, ISBN: 0444506128

Exam: AW5 (written final test)

Last update: 2023. 09. 25. 16:26